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Best CBD Cream of 2022 - Top 5 Brands for Lasting Muscle & Joint Pain Relief

If you’re searching for the newest thing in pain relief cream, there’s a good chance you’ve seen the acronym CBD.

Presented by Originated Media July 27, 2022

If you’re searching for the newest thing in pain relief cream, there’s a good chance you’ve seen the acronym CBD. CBD is short for cannabidiol, and it is derived from hemp plants. It’s been used in various formulations for hundreds of years, and CBD products today include everything from delicious gummy vitamins to CBD sports cream for injuries. 

When you are ready to explore alternative solutions to muscle aches and nerve pain and experience long-lasting pain relief, it’s time to explore these CBD cream brands. Our team of researchers and testers has taken the guesswork out of the equation and looked through dozens of products to find the best CBD cream products on the market. 

The Best CBD Creams: A Guide to CBD Pain Relief 

  1. CBDfx - Editor’s Choice: Best CBD Cream & Topical Products
  2. CBDistillery - Close Second: Great Daily Cream
  3. Green Roads - Runner-Up: Arthritic Pain Solution
  4. Receptra Naturals - Worthy Mention: Pain Remedy All-Rounder
  5. Aspen Green - Cooling Creams: Muscle Relief Champion

The Best CBD Cream Brands

1. CBDfx - Editor’s Choice: Best CBD Cream & Topical Products

CBDfx creates standout hemp-derived CBD products from organic hemp grown on American soil. The company was founded as a response to the crowded CBD topical marketplace. Instead of relying on fillers and low-quality CBD, CBDfx uses a CO2 extraction process that provides a pure, clean, and safe finished product. You won’t need to worry about the solvents and chemicals present in low-quality types of CBD pain cream. 

In addition to convenient topical products for joint pain and sore muscles, CBDfx offers gummies, oil tinctures, capsules, dog treats, balms, vape pens, drinks, edibles, and bundles that let you sample many products for a discount. CBDfx boasts over 43,700 verified five-star reviews across its products, and every topical CBD cream has been approved by a Medical Advisory Board of healthcare experts.  


CBDfx has over a dozen CBD creams and topical CBD products designed for external use to help relieve pain. One of the most popular picks is their CBD cream for pain, the CBDfx Muscle and Joint Cream Cooling Formula. This product comes in three different strengths and provides pain relief and a cooling sensation that feels fantastic. This CBD lotion is completely vegan and cruelty-free, so you can feel good using it. 

Are you active and on the go? CBDfx also turned their soothing cream into a convenient stick. The CBDfx Balm Stick Muscle & Joint Formula packs a powerful punch and comes in two concentrations, 750mg and 3,000mg. In addition to high-quality CBD oil, this balm stick contains essential oils that cool the skin like black pepper and wintergreen. Apply it in a jiffy to tackle neck pain, stiff joints, and arthritis aches without getting your hands dirty.


  • Cruelty-free
  • 60-day money-back guarantee
  • Made in the USA
  • Over 43,700 certified five-star reviews
  • Products designed and approved by a Medical Advisory Board


  • The CBD topical cream does not contain CBN 

Customers Are Talking About CBDfx

CBDfx is renowned for all of its full-spectrum CBD products, but the CBD cream for pain is a standout in customer reviews. Customers remarked on how the cooling essential oils helped the CBD cream work better, and they appreciate the convenient stick format. Some repeat buyers claim that CBDfx is the best CBD product to reduce pain.  

Find out more at CBDfx.com

2. CBDistillery - Close Second: Great Daily Cream

CBDistillery is not just interested in providing CBD creams and CBD topicals to adults of all ages—they care about starting a movement. CBDistillery creates high-quality hemp-derived CBD products that are designed based on research, rigorously third-party tested, and available in a comprehensive range of formats. With over 2 million happy customers, it’s easy to see why CBDistillery has carved out a name for itself. 

Whether you need pain relief, assistance getting enough sleep, or just want to experience the other health benefits of broad-spectrum CBD, CBDistillery has a product for you. Some of their most popular products include CBD oil, CBD chocolate, CBD soft gels, CBD gummies, CBD topicals, CBD powders, and even CBD pet products. Join the #CBDMOVEMENT with help from CBDistillery. 


CBDistillery CBD cream and CBD topical pain relief products come in a broad range of concentrations and formats. Their premium CBD cream is the CBDol Topical CBD Salve, and it’s a concentrated lotion that provides short-term pain relief after a hard workout or doing yard work. It was rated #1 for hemp-derived CBD salves in 2017 by High Times Magazine, and the accolades have not stopped pouring in since then. 

One of the more unique CBD creams that CBDistillery offers is CBD face cream and skincare products. This product is the best way to support healthy skin while receiving localized relief. The CBDistillery CBDefine Skin Care Cream has a base of nourishing coconut oil, tea tree oil, apricot oil, sunflower oil, and full-spectrum CBD. Looking beautiful and maintaining your skin has never been easier. 


  • 60-day satisfaction guarantee
  • Free shipping on orders over $75
  • Third-party laboratory results for every product
  • Non-GMO hemp oil
  • Variable mg of CBD for every product


  • They only offer full-spectrum CBD cream and not broad-spectrum CBD cream

Customers Are Talking About CBDistillery

CBDistillery is a popular choice for CBD cream and CBD topical salves because of the product versatility. Customers appreciate the pain relief that the CBD pain cream provides, in addition to the nourishing properties of their lotions for cracked skin. 

Find out more at TheCBDistillery.com

3. Green Roads - Runner-Up: Arthritic Pain Solution

When you have arthritis symptoms, it’s best to trust a healthcare professional with determining the best course of treatment. That’s why so many customers love Green Roads, which was founded by a pharmacist who was tired of prescribing creams and pills that got poor results and came laden with side effects. Every product that Green Roads offers, including their CBD cream for pain and CBD topicals, was designed by a pharmacist in line with strict quality standards.

Green Roads makes it simple to find the perfect solution for relaxation or pain relief, as they offer CBD gummies, CBD oil, nootropics, CBD coffee, CBD chocolate, CBD topical cream, and CBD products for pets. If you aren’t sure what is right for you, Green Roads makes it easy to sort products based on the type of relief you are looking for. 


The premier products that Green Roads offers for arthritic pain include the Arthritis Pain Relief Roll-On. This easy-to-apply ointment contains 1,500 mg of CBD in total. The blend includes soothing camphor, cooling menthol, four other anti-inflammatory botanical extracts, and broad-spectrum CBD. The convenient format makes the roll-on easy to stash in your gym bag or purse for everyday relief. 

If you’d prefer a more traditional CBD cream, the Green Roads Pain Relief CBD Cream is the perfect pick. This powerful, soothing cream rivals the strength of over-the-counter alternatives and contains a proprietary blend of menthol, methyl salicylate, fruit extracts, hemp-derived extracts, and more. The cream comes in different strengths and sizes, including a TSA-friendly .3 oz CBD cream. 


  • No animal testing
  • Founded and formulated by a health care professional
  • Broad-spectrum CBD and full-spectrum products
  • Discounts available for auto-delivery 
  • CBD cream and CBD oil in different concentrations


  • Products do not contain both CBD and CBN

Customers Are Talking About Green Roads

Customers keep coming back for more of Green Roads products because they provide prompt, on-the-go relief. Some buyers prefer the roll-on format because it instantly soothes pain at the gym or when on a walk with friends. Reviewers also mention the pleasant scent that is a contrast to many other products on the market. 

Find out more at GreenRoads.com

4. Receptra Naturals - Worthy Mention: Pain Remedy All-Rounder

Receptra Naturals cares about providing local jobs, growing high-quality Colorado hemp, and manufacturing the best CBD oil and CBD cream on the market. The founders take pride in knowing that the only time their CBD creams and CBD topicals leave the state is when they are in transit to your house! They have worked hard to develop a suite of CBD products that address a broad range of concerns including skin health, joint pain, insomnia, and stress. 

The Receptra Naturals product range includes CBD topicals, CBD capsules, CBD oil, gummies, CBD for pets, and customizable bundles. Each product is handcrafted with full-spectrum hemp extract from a Colorado-grown hemp plant, so you can feel good about the products you are putting in and on your body. 


The Receptra Naturals Serious Relief + Arnica Targeted Topical is one of the most versatile non-prescription CBD products on the market. It’s packed with 400 mg of CBD and contains high-quality, organic ingredients that ease muscle pain. This CBD topical has full-spectrum CBD, organic jojoba oil, and arnica that soothe and heal. The Serious Relief line is specially formulated for chronic pain and sensitive skin. 

Beyond the Serious Relief + Arnica Targeted Topical, Receptra Naturals also offers hydrating hemp body butter, relaxing body oil, and other salves. Each product offers targeted relief to handle existing irritation and prevent further aches and pains from developing. 


  • Free US shipping
  • Organic hemp that’s free from pesticides
  • Third-party testing
  • Made in the USA


  • Only available in one concentration

Customers Are Talking About Receptra Naturals Serious Relief + Arnica Targeted Topical

Customers love this targeted CBD topical for back pain and sore muscles, as it works quickly and provides ongoing relief. Many repeat buyers mention Receptra Naturals products as stronger than over-the-counter alternatives and having a light, pleasant scent that isn’t artificial. 

Find out more at ReceptraNaturals.com

5. Aspen Green - Cooling Creams: Muscle Relief Champion

Aspen Green is a leader in full-spectrum products, including CBD creams and CBD topicals. They were founded on the values of quality, integrity, and transparency, and they care about connecting adults just like you with organic hemp-derived products that let you live a pain-free, stress-free, healthy life. All Aspen Green products use hemp that is grown without pesticides on regulated farms, so they are free from toxins and filler. 

If you need a full-spectrum CBD solution, Aspen Green has a product for you. Aspen Green products include full-spectrum CBD oil in multiple concentrations, CBD cooling cream, CBD cream for pain, body oil, and gift sets that include multiple products. With USDA organic certification for most products, it’s simple to reap the benefits of CBD. 


Aspen Green CBD creams and CBD topical ointments are designed with soothing and comfort in mind. The Pain Relief Body Balm is a popular choice for dry and cracked skin, neck pain, back pain, and more. With full-spectrum hemp extract that was farmed and extracted in Colorado, their oil-based balms are a great way to stay healthy and feel better. As the base, Aspen Green uses moisturizing mango butter and beeswax. 

For an energizing experience, try the Muscle Relief Cooling Cream. This CBD cream for pain is formulated to ease tension, aches, muscle soreness, and knots all over the body. Beyond the full-spectrum hemp extract, this cream also contains organic jojoba oil, mango butter, arnica, menthol, and tea tree oil. Applying this CBD balm is simple, and it gets to work right away. 


  • FDA registered and cGMP certified
  • Third-party testing and verification
  • Grown in Colorado
  • QR-coded labels and boxes for quality assurance 
  • 60-day satisfaction guarantee


  • No roll-on CBD cream options

Customers Are Talking About Aspen Green

Aspen Green customers are enthusiastic about their CBD cream for pain and other CBD topical products. Many buyers initially used high doses of over-the-counter products before transitioning to a more natural and soothing alternative CBD cream. Beyond being safer, repeat buyers also love how quickly Aspen Green products work. 

Find out more at AspenGreen.com

How We Chose Our Top 5 CBD Cream Brands

It’s hard to be in pain and feel like prescription painkillers, over-the-counter drugs, and other chemical-laden options are your only choice. However, CBD topical creams are not formally tested and regulated by the government, so there is no quality guarantee without doing the right research and third-party verification into the CBD industry. We used a four-part system to evaluate all of the CBD cream options we featured in this article:

  1. Review the quality of the oil by examining third-party test results 
  2. Evaluate the efficacy of the CBD cream products for pain relief 
  3. Read through real customer reviews 
  4. Verify claims made by every company 

Thanks to this rigorous process designed to weigh the quality of each company selling CBD cream, you can shop with confidence. 

What is CBD Cream?

CBD cream is a safe, natural alternative to traditional pain relievers and insomnia medications. It is derived from hemp plants and has been found to offer many benefits, including increased relaxation, lower pain levels, and better sleep. 

CBD cream for pain works by interacting with different receptors that regulate your body, including things like serotonin receptors and pain receptors. By positively impacting the way that you feel, CBD lotion can ease existing pains and prevent new aches from starting.

While numerous types of CBD cream are available, full-spectrum CBD offers maximum potency and the benefits of the entourage effect. Hemp plants have dozens of different compounds that are shown to help with different things, from arthritis to insomnia. Full-spectrum CBD is extracted from the hemp in a manner that preserves all the cannabinoids, terpenes and other natural compounds. This is the best way to get true relief from acute or chronic pain when you apply CBD cream.  

The entourage effect in full–spectrum CBD cream relies on all of the small pieces that make hemp plants so special working together. If you choose a product that is CBD isolate instead of a full-spectrum or even broad-spectrum CBD lotion, there is a high chance you will be missing out on many of the benefits. 

What is CBD Cream Used For?

CBD cream is a versatile substance that helps CBD penetrate the surface of the skin by placing it in a water-based or oil-based cream. Once the CBD has a chance to soak in, you will feel the effects of CBD cream for pain from the surface of your skin to the deep muscles that are aching. Because most creams come with other ingredients to increase their efficacy, like coconut oil and aloe vera, they can be used for regular moisturizing in addition to pain relief. 

CBD topicals are safe and easy to use, and they are very popular for people who have chronic pain, those who like working out but hate being sore after, and active adults. CBD foot cream relieves itchy skin while helping you take a load off after a long day of spending time with family or standing on your feet at work. Because CBD is prescription drug-free, it’s easy to use in addition to existing soothing treatments in your routine.

How to Use CBD Cream

Topical CBD is applied externally to the surface of the skin and never swallowed or placed internally unless the manufacturer states that is safe. Read the directions on your CBD cream and use the appropriate amount on the part of your body that is in pain. Topical CBD is not dangerous, and it can be applied in addition to other products like transdermal patches. Every product has different effects, so wait until observing the effects of a first dose before applying a second dose.

How Long Does it Take for CBD Cream to Work?

Most CBD cream products take between 30-45 minutes to take effect. If you choose a CBD topical with other soothing ingredients like menthol or arnica, you will feel immediate cooling sensations as the cream gets to work. If you choose topical CBD products that have a high mg of CBD per dose, you should wait at least two hours before choosing to apply more. 

Is CBD Legal?

The Farm Bill made it legal to grow hemp and create broad-spectrum and full-spectrum CBD products. Hemp extracts and topical creams are legal to buy and sell in all 50 states, providing that they contain less than .3% THC. Every reputable manufacturer should have detailed information on their website for each product that states the precise concentration of CBD, other cannabinoids (including THC) as well as other ingredients that are present.

FAQ: The Best CBD Cream Brands  

Are there side effects to using CBD cream or CBD oil?

Compared with traditional over-the-counter medication, CBD topicals have very few side effects. However, there can be some side effects depending on the dosage you take and if you use topicals alongside other ingestible CBD products. Some of the side effects of CBD include drowsiness, changes in appetite, and diarrhea. Side effects are rare for CBD cream.

Is full-spectrum CBD or broad-spectrum CBD better?

In order to experience the full benefits of the entourage effect, it’s a good idea to choose a product with full-spectrum CBD. These products have all the pain-relief terpenes and positive compounds present in the hemp plant. For topicals, it is recommended that you do not choose a CBD isolate product. The three most common terms you will see when researching products include:


  • Full-spectrum CBD, which is CBD that still contains 0.3% of THC or less, terpenes, hemp compounds, and cannabinoids
  • Broad-spectrum CBD, which has no THC present but still has numerous other healthy hemp cannabinoids and terpenes
  • CBD isolate, which only has CBD and does not contain THC, terpenes, or other beneficial hemp compounds 


When should I use topicals? When should I use CBD oil instead?

Everyone metabolizes CBD differently, so some people prefer taking CBD oil and others prefer using CBD cream. Since both are approved nonprescription CBD products, you can use them separately or together. CBD drops or oils are great for daily use, before bed, or when you need to de-stress. Topical products work the best when applied directly to an area that is sore and offer powerful pain relief. 

What is the best time to use CBD cream?

CBD cream can be used at any time during the day or night, and it works best when you have a specific part of the body that requires relief. Topical products have surprising efficacy despite not being orally ingested, so you can anticipate the effects to last for multiple hours. If you have a particular injury or muscle soreness you are trying to treat, you can reapply your CBD cream numerous times to prevent pain from returning. 

Can you use CBD cream if you are pregnant or nursing?

While some products have a low mg of CBD per dosage, it is always best to check with your doctor before using them. 

Will CBD creams or oils impact my medications?

As with any other over-the-counter medication or supplement, it’s best to speak with your healthcare team before consuming CBD sublingually or through the skin. CBD is completely safe to use when purchased from a reputable manufacturer but having additional medical guidance will confirm that none of the other ingredients will interact with medications that you are already taking.

Do CBD products make you feel high?

No. Because CBD products are derived from hemp plants and have 0.3% THC or less, they will not make you feel high or intoxicated. One of the only side effects of CBD is drowsiness, so you feel more tired after ingesting CBD, but that is different from the “high” associated with marijuana and THC. Even if you take large doses of CBD, you will not experience a high. 

Can you use CBD cream for pain relief?

Many customers find that CBD is an effective way to ease pain, including pain from arthritis, injuries, and other ailments. There has been research performed on the connection between using CBD and experiencing pain relief, and as more studies happen, most industry experts anticipate this connection being strengthened even more. 

Are there other uses of CBD?

Yes! CBD is amazingly versatile, whether it’s found in a topical CBD cream form or in an oil or capsule. Based on scientific literature and many anecdotal experiences from loyal customers, some of the uses of CBD include:


  • Better sleep
  • Less inflammation
  • Lower stress levels
  • Anxiety relief
  • Lower pain levels 


Because there are so many ways to enjoy CBD today, it’s easy to find a product that allows you to benefit from natural terpenes and cannabinoids, whether it’s sweet berry gummies or a topical ointment. 

How can you choose the right CBD cream for your needs?

There are numerous factors that determine what cream or topical is best for your needs. As a rule of thumb, you should consider how the company extracts the CBD from hemp plants, what other ingredients are included in the cream, customer reviews, and what form of CBD you are interested in trying. 

Companies that grow and manufacture their products in the US are held to higher standards, and many use organic farming to prevent solvents and pesticides from entering any of the products. Any company with a good reputation will have laboratory testing results available on their website for every product. These results will show you exactly what is inside, so you don’t need to worry about too-high levels of THC or contaminants you never want to ingest. 

Additionally, the companies we’ve included in this guide to the best CBD cream have products available in a broad range of price points. Many companies offer bundles and samplers to allow you to try products before buying a larger size. Some even have 60-day money-back guarantees, so you can make sure that the CBD cream works well for your needs. 

Will CBD cream use show up on a drug test?

CBD products contain levels of THC below 0.3%, but drug tests are designed solely to detect THC and not CBD. Particularly if you are consuming full-spectrum CBD oils, gummies, and other products, there is a chance that your test might mistake CBD usage for THC usage. It’s best to speak with your employer about your CBD use so that they understand your test results. If you are very concerned about your drug test or unable to have any THC, choose a CBD isolate product. 

Most manufacturers display detailed test results on their websites. When you are worried about CBD being in your urine or blood, check third-party laboratory tests to confirm that advertised levels of THC are accurate. 

Can you travel with CBD topicals?

Providing that you are traveling domestically, CBD products that contain 0.3% or less THC are completely legal because of the 2018 Farm Bill. Make sure that your cream is in a container that meets TSA standards if you are boarding a plane. When traveling internationally, check the laws of each country that you will be stopping in to make sure that CBD products are not regulated. 

Do you need a prescription to use or receive CBD?

No! CBD is not a prescription medication, and it is legal to produce and consume because of the 2018 Farm Bill. There are prescription medications that use hemp-derived compounds, but the CBD cream options as well as other products available on the websites listed above can be sold and used safely by any adult. 

If you already take prescription medication, check with your doctor before adding CBD to your daily routine. Because it is safe and well-researched, there is a high chance your doctor will encourage it.

What are terpenes?

Terpenes are one of the things that makes CBD so magical. These compounds occur naturally in hemp plants, and they each have different smells and flavors that add to what most people traditionally associate with Cannabis sativa. The distillation process is designed to preserve terpene content so that every user can receive maximum benefits. 

Different terpenes are associated with different health effects, For example, one of the most powerful terpenes is known as Myrcene. This terpene helps improve relaxation and ease pain. That is just one of the dozens of terpenes present in a single CBD product. 

What CBD Cream is the Best?

It can be hard to live with chronic pain, arthritis, and persistent injuries that prevent you from living your life the way that you want to. One of the best ways to preserve your well-being and stay active as you age is CBD cream. Premium CBD cream containing the full benefits of terpenes will soothe your skin, moisturize your body, and penetrate deep below the surface for better pain relief. 

All the high-quality products featured in this blog are better ways to manage your pain, and they come without the long lists of side effects that over-the-counter supplements and prescription medications do. Our favorite brand for CBD topicals and Editor’s Choice was CBDfx. This company is at the forefront of innovation for creams and lotions that get real results.

We encourage you to experiment with all of the prestigious brands featured in this article to find the perfect solution for your pain, sleep easier, and live a better life.