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Best Brain Supplements of 2023: Enhance Your Cognitive Function

Brain supplements can improve focus, clarity, alertness, and overall cognitive performance.

Presented by Originated Media February 16, 2023

Boosting brain power for better cognitive function is a priority for many people, not just those of us in the getting-up-there demographic, and the best brain supplements offer an effective way to do this. Brain supplements can improve focus, clarity, alertness, and overall cognitive performance by providing essential nutrients such as omega-3 fatty acids, vitamin B12, and other vital components.

The problem is, there are so many products sold online claiming to work "miracles", how are you supposed to know which brain supplements are best? And even if you know how to spot a great product, you may be uncertain about the best dosage and duration of use.

To help cut through the confusion and make an informed decision, we've created this comprehensive buyer's guide to the best brain supplements. With detailed product reviews, handy usage tips and in-depth FAQs, you'll have everything needed to make the best choice for your cognitive health goals.

4 Best Brain Supplements

1. NooCube – Overall Best of the Best Brain Supplements

2. Hunter Evolve - Best for High-Performance Individuals

3. Onnit - Best Allergen-Free Supplements

4. Natural Stacks - Best Fast-Acting Formula

Best Brain Supplements Reviewed

1. NooCube – Overall Best of the Best Brain Supplements


  • Contains 13 science-backed ingredients
  • No prescription needed
  • Clinically proven results
  • No harmful side effects


  • None

Manufacturer Info

Wolfson Brands, a well-known and highly-reputable UK wellness company, manufactures NooCube. This wellness brand is best known for its range of high-quality dietary supplements and natural health products, which they've produced for many years.

When it comes to their brain supplements, the manufacturer takes no shortcuts. All of the ingredients used in NooCube are thoroughly tested for purity and potency, so you can rest assured that what you're getting to improve your brain health is the best quality available.

About NooCube

When it comes to boosting the brain’s power without harmful side effects, nothing beats NooCube's clinically proven formula. With 13 science-backed ingredients enhancing cognitive speed and accuracy, NooCube is highly effective for improving focus, memory recall, concentration, and overall brain performance.

In a clinical trial lasting 12 months, most users reported a significant improvement in cognitive performance and brain functions, as well as a reduction in procrastination behaviors that keep them from reaching their best.

The secret ingredient in the formula is the brand's proprietary marigold extract. It contains lutein and isomers known to stimulate the brain and enhance cognitive function. Supporting this is a powerful blend of natural nootropics, amino acids, choline, and vitamins. With this potent combination of ingredients, NooCube delivers fast-acting brain power in no time.

Bottles are available in single and bulk options, with significant savings achieved for larger orders. Each bottle contains 60 capsules (one month's supply) that go down easy with water, juice, or your favorite beverage.

Why We Like NooCube

Whether you are sluggish at the office, suffering from brain fog, or simply looking to get the best out of your cognitive potential, NooCube can help get you back to peak performance. The best brain supplement on the market, NooCube has been proven clinically to improve memory recall, focus, clarity of thought, and overall cognitive performance. With no dangerous side effects or prescription drugs needed, you can trust NooCube to deliver a safe and effective solution for enhancing your best mental abilities.

Learn more about NooCube

2. Hunter Evolve - Best for High-Performance Individuals


  • Uses safe, tested ingredients
  • Boosts energy levels
  • High potency
  • Evidence-based formulation


  • Requires larger amount of capsules per day than others on this list

Manufacturer Info

Roar Ambition manufactures Hunter Evolve, a brand best known for producing science-backed supplements that help athletes and high-performance individuals reach their best. The brand understands the importance of getting results without compromising on quality or safety, and they don't cut corners when it comes to ingredient selection.

Additionally, the brand utilizes the best in manufacturing practices with cGMP certification, third-party testing, and a 100% satisfaction guarantee. Dedicated to keeping customers well-informed, all of their best brain supplements include detailed information on the ingredients and their benefits.

About Hunter Evolve

Designed to help you reach peak cognitive performance, Hunter Evolve Focus is a powerful nootropic supplement that packs a punch in just one capsule. Our best brain supplement for boosting energy levels and focus, Hunter Evolve Focus contains natural ingredients backed by science to safely improve cognitive performance.

Hunter Evolve Focus is best used if you're looking for a push in the gym and on the job. The powerful combination of citicoline, lion's mane, L-tyrosine, and L-theanine helps to boost energy levels while promoting a state of calm alertness.

Using Focus can help you maximize productivity without sacrificing mental clarity or focus. And best of all, all the ingredients used in these best brain supplements are thoroughly tested for purity and potency, so you know you're getting the best quality available for your brain health.

One, two, and four-month bundles are available with free gifts for larger orders. For those not sure how much to buy or how best to get started, the Hunter Evolve website offers helpful advice in the FAQ section.

Why We Like Hunter Evolve

As a nootropic supplement designed to help busy professionals and athletes reach peak performance, Hunter Evolve Focus is best for those needing an extra push. The blend of natural ingredients is backed by science, ensuring you get the best cognitive performance without compromising safety or quality. 

With evidence-based formulations, cGMP certification, and third-party testing, you can trust that Hunter Evolve's Focus supplements will help you reach your best.

Learn more about Hunter Evolve

3. Onnit - Best Allergen-Free Brain Supplements


  • Free from all major allergens
  • Suitable for multiple dietary lifestyles
  • Supports focus and mental processing
  • Contains no caffeine


  • Better pricing available with subscription orders

Manufacturer Info

Onnit brain supplements are made in-house by the Onnit Labs team, best known for their top-tier health and fitness products. Onnit is committed to producing quality supplements free from major allergens like gluten, dairy, soy, and nuts.

Additionally, they source only the best ingredients with a sustainability-minded process that supports the ability of customers to trust they are getting the best brain supplement available. And with detailed information about the ingredients and benefits on each product page, buyers can be confident they are getting the right supplement for their brain health.

About Onnit

Onnit brain supplements are best for those looking for an allergen-free supplement that supports cognitive function without the use of caffeine or other stimulants. Their supplements feature a blend of natural ingredients that help you go with the flow and make better decisions.

This brain supplement contains ingredients like Alpha-GPC, L-theanine, cat’s claw and vitamin B6 that work together to promote focus, clarity of thinking, and improved cognitive processing. All these ingredients are rigorously tested for purity and potency by a third-party lab for the highest quality brain supplement available.

Additionally, their formula includes mood-balancing ingredients that promote overall brain health by helping to reduce stress and anxiety. With Onnit supplements for boosting brain functions, you'll never have to worry about the brain fog or jitters associated with caffeine and other focus products.

Single orders are available in 90-count bottles, but the best savings comes with bulk and subscription orders. These special offers provide an easy and convenient way to save on supplements without sacrificing quality or results - plus, they come with free goodies that help prolong the brain-boosting effects of the supplements.

Why We Like Onnit

Onnit brain boosters are best for those who need an allergen-free brain supplement that helps improve cognitive function safely and naturally. The ingredients are carefully chosen to help promote mental clarity and focus while avoiding any use of caffeine or stimulants.

Learn more about Onnit

4. Natural Stacks - Best Fast-Acting Formula


  • Supercharges neurotransmitters
  • All-natural formula
  • Fast results after first serving
  • Gluten-free & vegan


  • No free gifts with purchase

Manufacturer Info

The wellness brand Natural Stacks is known for producing supplements specifically designed to support specific wellness issues. From mood boosters to sleep aids to energy boosters, Natural Stacks uses all-natural ingredients to create powerful supplements that work fast.

Whether it is the brand's brain supplement or one of its many other products, users can be assured of the best in quality and safety. Natural Stacks uses the most effective non-GMO, gluten-free and vegan ingredients in every supplement – all of which are third-party tested for potency and purity.

About Natural Stacks Brain Supplement

NeuroFuel is the Natural Stacks brain supplement designed to supercharge your neurotransmitters for improved focus, clarity, and mental performance. This fast-acting formula utilizes several all-natural ingredients that work together to provide a powerful yet balanced blend of cognitive enhancers.

It's the artichoke extract and L-phenylalanine that helps to trigger the release of key neurotransmitters for improved focus and mental clarity. The supplement also includes forskolin and L-carnitine, which help to increase energy levels and reduce fatigue.

The NeuroFuel formula is free of gluten, dairy, soy, and nuts - making it ideal for those with food allergies or sensitivities. It's also vegan-friendly and paleo-friendly, making it an excellent choice for any health-conscious customer.

Users can take 1 to 3 capsules a day from the 45-count bottle. Single orders have a higher price point than subscription orders and do not include membership benefits such as free shipping, a 20% discount on all orders, and flexible delivery options.

Why We Like Natural Stacks

The NeuroFuel supplement from Natural Stacks is perfect for those looking for powerful brain boosters that work fast. The all-natural formula helps boost neurotransmitters and improve mental clarity and performance - without using stimulants or harmful additives. Additionally, the supplement is vegan and paleo, making it a great choice for those already following a specific wellness or diet routine.

Learn more at Natural Stacks

How We Made Our List of the Best Brain Health Supplements

Searching through the thousands of brain health supplements to find the best was no easy task. Our extensive research started with a deep dive into what makes a brain health supplement effective, safe, and reliable.

After determining that natural ingredients that help brain cells produce more energy and enhance focus were essential, we looked into the different types of brain health supplements.

From multi-ingredient formulas to single-ingredient formulas, we evaluated each supplement based on its effectiveness and safety. We then narrowed down our list by assessing various factors such as customer reviews, brand reputation, third-party certifications (GMP/NSF/USP), price, and manufacturing process.

We then put a short list of products to the test, checking to see if our research matched our own experiences. After extensive analysis of the results, we became confident that the four products on this list represent the best way to boost brain power for a more productive and healthy life.

What Are Brain Supplements?

Often referred to as nootropics, products that promote brain health are dietary supplements designed to improve cognitive function. They are formulated to enhance neurotransmitter performance, improve memory retention, and help the brain become more efficient at processing information.

The key to maximizing brain health and function lies in the quality of the ingredients and their combinations. Though products vary in their specific formulation, key ingredients found in the best supplements to boost brain performance include:

  • Lutein - A neurotransmitter often associated with improved focus, concentration, and memory.
  • Ginkgo Biloba - Known for its antioxidant properties, it has been used for centuries to boost brain and cognitive function.
  • Tyrosine - An amino acid that is essential for the production of dopamine which helps with alertness, mental focus, and motivation.
  • Omega-3 Fatty Acids - Research has linked Omega-3 fatty acids to improved cognitive function, memory processing, and brain health.
  • Vitamin B6 - A water-soluble vitamin that helps support the nervous system and maintain brain cells.
  • Phenylalanine - An amino acid linked to improved mood and cognitive alertness.

For these ingredients to work, they need to be present in the right ratios and delivered in a way that the body can easily absorb. For this reason, most supplements that support brain health are available in easy-to-swallow capsules specifically designed to maximize absorption in the body.

What To Consider When Buying Quality Brain Supplements

Understanding how to separate high-quality nootropics products from hyped-up products doesn't mean that the ones you pick will work for your brain health goals. Be sure to keep the following in mind before purchasing to ensure that the supplements you buy to boost your brain performance and overall brain health are right for you.

Know what you want to achieve with your supplement

Are you hoping to improve cognitive function? Boost memory retention? Enhance focus and motivation? Stay alert? Knowing your goal will help you determine which type of supplement would best suit your needs.

The reason is that some products have additional ingredients designed to support specific wellness needs in addition to boosting brain power. From natural herbs, vitamins, and minerals to amino acids and essential fatty acids, understanding the various types of brain supplements available - and their effects - will make it easier to pick the right one.

Typically, those needing an energy boost as part of their brain health routine will opt for products containing guarana, caffeine, and other natural stimulants. In contrast, those looking to improve cognitive function and mental clarity might opt for a more nutrient-dense formula.

Know how often you want to take your supplement

Every nootropic brain supplement has varied dosing to ensure you get the most out of the product. Unfortunately, some require dosing several capsules many times a day, and others require a single capsule daily or as needed. By knowing how often you want to take your supplement, you can find one with a dosing schedule that fits your lifestyle.

Most supplements require one to two doses per day and are sold in 60 to 90-count bottles. These are perfect for short-term use and allow for flexibility with your dosing schedule. However, if you plan on taking your supplement regularly for an extended period of time, it might be worth investing in a larger bottle, as these products typically come at a discounted rate.

Research the company that produces the supplement

When selecting the best brain supplements, it's clearly important to ensure that the company producing them is reputable and transparent. Reputable companies will always include an ingredient list, dosage instructions, safety warnings, and laboratory testing results on their website or product packaging - and offer a money-back guarantee if you're unsatisfied with your purchase.

Furthermore, you should verify that the company is subject to current Good Manufacturing Practices (cGMP) and that they use independent third-party testing of their products. This will help you be confident that the product is safe, effective, and free from contaminants.

How To Take Brain Supplements?

Taking supplements to boost cognitive ability is relatively straightforward and really only requires adherence to a regimented dosing schedule. By taking the supplements at the same time every day, your body can adjust and recognize when it is time to absorb the essential nutrients needed to support brain health.

Most nootropic supplements are available in capsule form and are typically taken 1-3 times a day, with meals or after meals. For best results, take the supplement consistently for at least 4 weeks before evaluating any changes in cognitive function.

It is important to stay hydrated when taking these supplements, as the increased energy levels can lead to dehydration. It is also essential to get adequate sleep and maintain a balanced diet, as both have been proven to help support better brain health.

Most users will likely want to take these products in the morning, about an hour or so before they need to be in peak mental performance, and then again in the afternoon to sustain their focus. Although everyone’s body is different, some users may want to adjust the times for the best results.

What are the Benefits of Brain Supplements?

To understand the benefits of supplements that enhance cognitive ability, focus, and memory, it is essential first to understand why we need these supplements in the first place.

The human brain is absolutely extraordinary, but it needs certain vitamins, minerals, nutrients, and amino acids to stay in top form. While many of these compounds get naturally produced through diet and exercise, some need to be supplemented - especially as we age and brain function declines.

Additionally, because of everyday stresses that pollute our bodies with toxins, many of us don't get the essential brain-boosting nutrients our brains need to function properly. 

This is when cognitive enhancing supplements come in handy - they provide a concentrated dose of brain-boosting vitamins and minerals to help support the most essential cognitive functions.

Enhanced memory recall

Ever forget what you were going to do or say? Brain health supplements can help with that. Neuro-nutrient support helps to promote better communication between the cells in your brain, which leads to improved overall cognitive function and memory recall. That includes remembering names, facts, numbers, and more.

Improved concentration & focus

We all know how difficult it is to stay alert throughout the day as we juggle multiple tasks at once. Nootropic supplements can help support cognitive function by increasing your ability to concentrate for extended periods of time. They can also help reduce cognitive fatigue and support your brain's ability to respond quickly and accurately.

Sharper decision making

For any successful business, good decision-making is essential. Nootropic brain-boosting supplements can help improve your reasoning skills by boosting mental clarity and focus - allowing you to make decisions more quickly and accurately.

Improved mood

The key ingredients that support better brain health also work to stimulate dopamine and serotonin receptors responsible for regulating emotion and motivation. As a result, many people find that taking brain-boosters can help them to feel more focused, energized, and positive - helping to improve overall mood.

Better physical performance

While brain function and physical performance are two separate things, they're often connected. When you feel energized and focused, your physical performance will also improve. Taking brain-boosting supplements can help increase energy levels and focus - allowing you to be more productive and efficient in whatever task you take on - from weight training to outdoor running.

What Does It Feel Like When You Boost Brain Function?

While nootropic brain-boosting supplements can help you work, perform, and think more efficiently, most users won’t experience any immediate changes. Unlike the effects of caffeine, which can be felt within minutes after consumption, changes in cognitive ability from brain-boosting supplements take longer to manifest.

Depending on your supplement regimen and reasons for use, there are a few different ways you might feel when taking brain-boosting supplements. 

For example, those taking supplements as part of a general wellness routine may start to notice effects like improved short-term memory, quicker recall time when learning new information, and improved focus during tasks within a few weeks of use.

For those taking nootropics for athletic performance, an increase in energy levels should be evident shortly after use, usually within two hours. This can lead to enhanced physical performance that is sustained over a longer period of time.

Users consuming brain boosters for specific situations like a big meeting or test should experience the effects within 1-2 hours of taking the supplement. This should give them a sharp focus and enhanced cognitive abilities to help them take on any task that comes their way.

While effects may vary depending on the person and formula, users rarely report effects that leave them feeling high or unable to control themselves. With nootropic ingredients being natural herbal extracts or vitamins, the effects are much more subtle and rarely cause extreme reactions.

Are Brain Boosters and Performance Enhancers the Same?

There is a lot of confusion surrounding the difference between brain boosters and performance enhancers, as the two are often grouped together as "cognitive enhancers".

Brain boosters are supplements that improve the brain's overall health and function. Although some nootropics may have benefits for athletes, such as enhanced focus and energy levels, their primary purpose is to enhance cognitive abilities rather than physical performance.

On the other hand, performance enhancers are specifically designed to increase muscle strength and endurance in athletes. These supplements typically contain ingredients like caffeine or creatine that can boost energy levels, improve reaction time and focus, and help athletes push their limits.

Brain boosters usually contain natural ingredients compared to the synthetic ingredients found in performance enhancers, so they can be taken without the risk of side effects. Performance enhancers, however, may come with some unwanted side effects and should be used carefully and only under strict supervision.

Ultimately, if your goal is to get better support for brain function and health, brain boosters are the way to go. They are specifically designed for cognitive enhancement and offer numerous benefits compared to performance enhancers. With the right formula and regular use, brain boosters can help users reach their full mental potential and stay sharp for day-to-day tasks.

Are Brain Supplements Safe?

Supplements that boost brain performance are generally accepted as safe. Products from top brands are typically made from all-natural ingredients that are allergen-free, vegan, and non-GMO.

That being said, just because a product is all-natural doesn't mean it is without risks or side effects. Fortunately, though, side effects associated with brain boosting pills or supplements are typically mild and include:

  • headaches
  • nausea
  • upset stomach
  • changes in vision
  • fluctuation in body temperature

Many of these side effects result from the body adjusting to the new substances entering your system. Sometimes, side effects may occur if capsule supplements are taken without adequate food or water.

No matter your reason for taking them, or the type you are taking, it is always recommended to speak to a doctor before taking any wellness supplements. Nootropic products can interact with certain medications and conditions, and a licensed medical professional will best be able to identify any potential risks.

Frequently Asked Questions

1. How many brain supplement capsules should I take a day?

The right amount of capsules to take per day will depend on the type and dosage of the brain supplement. Be sure to read the label to get an idea of how many capsules you need to take daily, and adjust accordingly if needed.

2. How long do brain-boosting supplements take to work?

The effects of supplements will vary depending on the particular formula as well as the individual user. Generally, however, supplements to support optimal brain function should start to show some effects within two weeks of regular use. However, some fast-acting formulas can start working in as little as 30 minutes.

3. Can you take supplements for brain function while pregnant?

It is not recommended to take supplements that boost brain functions while pregnant, as there are potential risks that have not been fully explored. If you are looking for brain support during pregnancy, it's important to talk with your doctor about safe and healthy alternatives.

4. Are brain boosters bad for you?

Brain boosters are generally safe and have few side effects if taken in the recommended dosage. However, it's important to consult your doctor before taking brain boosters, especially if you are pregnant or have any medical conditions that need to be considered.

5. Are brain-boosting supplements legal?

Yes, supplements to boost brain functions are legal and can be found in most health stores and online retailers. While not regulated by the FDA, many regulatory agencies work to set high standards in the industry, ensuring users get the best supplements for healthy brain function on the market.

6. Are brain boosters addictive?

Generally, brain boosters are not addictive and can be taken as needed or on a regular basis. However, it's important to stick to the recommended dosage and speak with your doctor if you have any concerns. Additionally, these supplements should not replace healthy lifestyle habits such as good sleep, nutrition, and exercise.

Better Brain Function With High-Quality Brain Boosters

Brain boosters are a great way to support brain health and enhance brain function. When taken correctly, they can provide numerous benefits, such as improved memory, focus, concentration, and overall mental well-being. Plus, brain boosters contain natural ingredients that don't come with the same risks associated with some performance enhancers.

Whether it's long-lasting support or short-term help when you need it most, the best brain supplements on this list ensure effective results without the risks of adverse side effects. So, check out our top brain boosters today, and take the next step towards a healthier, better-functioning brain.